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Mechanistic analysis of Zein nanoparticles/PLGA triblock in situ forming implants for glimepiride

OBJECTIVES: The study aims at applying pharmaceutical nanotechnology and D-optimal fractional factorial design to screen and optimize the high-risk variables affecting the performance of a complex drug delivery system consisting of glimepiride–Zein nanoparticles and inclusion of the optimized formul...

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Detalles Bibliográficos
Autores principales:	Ahmed, Osama Abdelhakim Aly, Zidan, Ahmed Samir, Khayat, Maan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745829/ https://www.ncbi.nlm.nih.gov/pubmed/26893561 http://dx.doi.org/10.2147/IJN.S99731

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