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Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats

BACKGROUND: In the pathogenesis of herpes simplex keratitis, herpes simplex virus type 1 (HSV-1) infection begins in corneal epithelium cells and then progresses through the sensory nerve endings and finally travels up forward to the trigeminal ganglion (TG), where it remains as latent virus. The av...

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Detalles Bibliográficos
Autores principales: Xu, Kun, Pan, Shi-Yin, Song, Jin-Xin, Liu, Xian-Ning, An, Na, Zheng, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745838/
https://www.ncbi.nlm.nih.gov/pubmed/26893545
http://dx.doi.org/10.2147/DDDT.S96730