Characterization of an oncolytic adenovirus vector constructed to target the cMet receptor

The cMet receptor is a homodimer with tyrosine kinase activity. Upon stimulation with its ligand, hepatocyte growth factor (HGF), the receptor mediates wide physiologic actions. The HGF-cMet signaling pathway is dysregulated in many cancers, which makes cMet an important target for novel therapeutic...

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Detalles Bibliográficos
Autores principales: Sakr, Hany I, Coleman, David T, Cardelli, James A, Mathis, J Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746000/
https://www.ncbi.nlm.nih.gov/pubmed/26866014
http://dx.doi.org/10.2147/OV.S87369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746000/
https://www.ncbi.nlm.nih.gov/pubmed/26866014
http://dx.doi.org/10.2147/OV.S87369

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