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CAUSEL: An epigenome and genome editing pipeline for establishing function of non-coding GWAS variants
The vast majority of disease-associated single nucleotide polymorphisms (SNPs) mapped by genome-wide association studies (GWAS) are located in the non-protein coding genome, but establishing the functional and mechanistic roles of these sequence variants has proven challenging. Here, we describe a g...
Príomhchruthaitheoirí: | , , , , , , , , , , , , , , , , , , |
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Formáid: | Online Alt Téacs |
Teanga: | English |
Foilsithe / Cruthaithe: |
2015
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Ábhair: | |
Rochtain ar líne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746056/ https://www.ncbi.nlm.nih.gov/pubmed/26398868 http://dx.doi.org/10.1038/nm.3975 |