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Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo

BACKGROUND: Small cell lung cancer (SCLC) is an extremely aggressive disease, commonly displaying therapy-resistant relapse. We have previously identified neuroendocrine and epithelial phenotypes in SCLC tumours and the neuroendocrine marker, pro-opiomelanocortin (POMC), correlated with worse overal...

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Detalles Bibliográficos
Autores principales: Meredith, Suzanne L., Bryant, Jennifer L., Babur, Muhammad, Riddell, Philip W., Behrouzi, Roya, Williams, Kaye J., White, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746075/
https://www.ncbi.nlm.nih.gov/pubmed/26848743
http://dx.doi.org/10.1371/journal.pone.0148404