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Functional Analysis of the Citrate Activator CitO from Enterococcus faecalis Implicates a Divalent Metal in Ligand Binding

The regulator of citrate metabolism, CitO, from Enterococcus faecalis belongs to the FCD family within the GntR superfamily. In the presence of citrate, CitO binds to cis-acting sequences located upstream of the cit promoters inducing the expression of genes involved in citrate utilization. The quan...

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Detalles Bibliográficos
Autores principales: Blancato, Víctor S., Pagliai, Fernando A., Magni, Christian, Gonzalez, Claudio F., Lorca, Graciela L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746285/
https://www.ncbi.nlm.nih.gov/pubmed/26903980
http://dx.doi.org/10.3389/fmicb.2016.00101