Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line

Acetaminophen (APAP) is a safe analgesic antipyretic drug at prescribed doses. Its overdose, however, can cause life-threatening liver damage. Though, involvement of oxidative stress is widely acknowledged in APAP-induced hepatocellular death, the mechanism of this increased oxidative stress and the...

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Detalles Bibliográficos
Autores principales: Badr, Heba, Kozai, Daisuke, Sakaguchi, Reiko, Numata, Tomohiro, Mori, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746322/
https://www.ncbi.nlm.nih.gov/pubmed/26903865
http://dx.doi.org/10.3389/fphar.2016.00019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746322/
https://www.ncbi.nlm.nih.gov/pubmed/26903865
http://dx.doi.org/10.3389/fphar.2016.00019

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