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Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia

Sepsis-associated encephalopathy (SAE) is characterized as brain dysfunction associated with sepsis. In this study we sought to investigate the effects of resveratrol in mice with SAE, as well as its effects in NLRP3 inflammasome and IL-1β, which were critical in the pathogenesis of SAE. SAE was ind...

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Detalles Bibliográficos
Autores principales: Sui, Da-ming, Xie, Qun, Yi, Wen-jing, Gupta, Sahil, Yu, Xi-ya, Li, Jin-bao, Wang, Jun, Wang, Jia-feng, Deng, Xiao-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746398/
https://www.ncbi.nlm.nih.gov/pubmed/26924896
http://dx.doi.org/10.1155/2016/1045657