KIR haplotypes are associated with late-onset type 1 diabetes in European–American families

Classical human leukocyte antigens (HLA) genes confer the strongest, but not the only, genetic susceptibility to type 1 diabetes. Killer cell immunoglobulin-like receptors (KIR), on natural killer (NK) cells, bind ligands including class I HLA. We examined presence or absence, with copy number, of K...

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Detalles Bibliográficos
Autores principales: Traherne, J A, Jiang, W, Valdes, A M, Hollenbach, J A, Jayaraman, J, Lane, J A, Johnson, C, Trowsdale, J, Noble, J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746488/
https://www.ncbi.nlm.nih.gov/pubmed/26492518
http://dx.doi.org/10.1038/gene.2015.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746488/
https://www.ncbi.nlm.nih.gov/pubmed/26492518
http://dx.doi.org/10.1038/gene.2015.44

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