The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness

Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments is an emerging...

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Detalles Bibliográficos
Autores principales: Ouni, M, Belot, M P, Castell, A L, Fradin, D, Bougnères, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746489/
https://www.ncbi.nlm.nih.gov/pubmed/25869012
http://dx.doi.org/10.1038/tpj.2015.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746489/
https://www.ncbi.nlm.nih.gov/pubmed/25869012
http://dx.doi.org/10.1038/tpj.2015.26

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