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The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness
Short children using growth hormone (GH) to accelerate their growth respond to this treatment with a variable efficacy. The causes of this individual variability are multifactorial and could involve epigenetics. Quantifying the impact of epigenetic variation on response to treatments is an emerging...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746489/ https://www.ncbi.nlm.nih.gov/pubmed/25869012 http://dx.doi.org/10.1038/tpj.2015.26 |