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Lithium inhibits tumor lymphangiogenesis and metastasis through the inhibition of TGFBIp expression in cancer cells

Metastasis is the main cause of mortality in cancer patients. Although there are many anti-cancer drugs targeting tumor growth, anti-metastatic agents are rarely developed. Angiogenesis and lymphangiogenesis are crucial for cancer progression; in particular, lymphangiogenesis is pivotal for metastas...

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Detalles Bibliográficos
Autores principales: Maeng, Yong-Sun, Lee, Rina, Lee, Boram, Choi, Seung-il, Kim, Eung Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746585/
https://www.ncbi.nlm.nih.gov/pubmed/26857144
http://dx.doi.org/10.1038/srep20739