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Human monocytes undergo functional re-programming during differentiation to dendritic cell mediated by human extravillous trophoblasts
Maternal immune adaptation is required for a successful pregnancy to avoid rejection of the fetal–placental unit. Dendritic cells within the decidual microenvironment lock in a tolerogenic profile. However, how these tolerogenic DCs are induced and the underlying mechanisms are largely unknown. In t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746586/ https://www.ncbi.nlm.nih.gov/pubmed/26857012 http://dx.doi.org/10.1038/srep20409 |