Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance

Bif-1 is a membrane-curvature inducing protein that is implicated in the regulation of autophagy and tumorigenesis. Here, we report that Bif-1 plays a critical role in regulating lipid catabolism to control the size of lipid droplets and prevent the development of obesity and insulin resistance upon...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Takahashi, Yoshinori, Desai, Neelam, Zhang, Jun, Serfass, Jacob M., Shi, Yu-Guang, Lynch, Christopher J., Wang, Hong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746598/
https://www.ncbi.nlm.nih.gov/pubmed/26857140
http://dx.doi.org/10.1038/srep20453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746598/
https://www.ncbi.nlm.nih.gov/pubmed/26857140
http://dx.doi.org/10.1038/srep20453

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