Cargando…

The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin

Differentiation of inflammatory macrophages from monocytes is characterized by an orderly integration of epigenetic and transcriptional regulatory mechanisms guided by lineage-determining transcription factors such as PU.1. Further activation of macrophages leads to a stimulus- or microenvironment-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Susanne V, Krebs, Wolfgang, Ulas, Thomas, Xue, Jia, Baßler, Kevin, Günther, Patrick, Hardt, Anna-Lena, Schultze, Hartmut, Sander, Jil, Klee, Kathrin, Theis, Heidi, Kraut, Michael, Beyer, Marc, Schultze, Joachim L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746609/
https://www.ncbi.nlm.nih.gov/pubmed/26729620
http://dx.doi.org/10.1038/cr.2016.1