Cargando…
The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin
Differentiation of inflammatory macrophages from monocytes is characterized by an orderly integration of epigenetic and transcriptional regulatory mechanisms guided by lineage-determining transcription factors such as PU.1. Further activation of macrophages leads to a stimulus- or microenvironment-s...
Autores principales: | Schmidt, Susanne V, Krebs, Wolfgang, Ulas, Thomas, Xue, Jia, Baßler, Kevin, Günther, Patrick, Hardt, Anna-Lena, Schultze, Hartmut, Sander, Jil, Klee, Kathrin, Theis, Heidi, Kraut, Michael, Beyer, Marc, Schultze, Joachim L |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746609/ https://www.ncbi.nlm.nih.gov/pubmed/26729620 http://dx.doi.org/10.1038/cr.2016.1 |
Ejemplares similares
-
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
por: Xue, Jia, et al.
Publicado: (2014) -
Optimization of transcription factor binding map accuracy utilizing knockout-mouse models
por: Krebs, Wolfgang, et al.
Publicado: (2014) -
High-Resolution Transcriptome of Human Macrophages
por: Beyer, Marc, et al.
Publicado: (2012) -
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2
por: Sander, Jil, et al.
Publicado: (2017) -
Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients
por: Tuit, Sander, et al.
Publicado: (2019)