RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes

RNA-binding motif protein 4a (RBM4a) reportedly reprograms splicing profiles of the insulin receptor (IR) and myocyte enhancer factor 2C (MEF2C) genes, facilitating the differentiation of brown adipocytes. Using an RNA-sequencing analysis, we first compared the gene expressing profiles between wild-...

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Detalles Bibliográficos
Autores principales: Lin, Jung-Chun, Lu, Yi-Han, Liu, Yun-Ru, Lin, Ying-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746625/
https://www.ncbi.nlm.nih.gov/pubmed/26857472
http://dx.doi.org/10.1038/srep20665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746625/
https://www.ncbi.nlm.nih.gov/pubmed/26857472
http://dx.doi.org/10.1038/srep20665

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