Cargando…
RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes
RNA-binding motif protein 4a (RBM4a) reportedly reprograms splicing profiles of the insulin receptor (IR) and myocyte enhancer factor 2C (MEF2C) genes, facilitating the differentiation of brown adipocytes. Using an RNA-sequencing analysis, we first compared the gene expressing profiles between wild-...
Autores principales: | Lin, Jung-Chun, Lu, Yi-Han, Liu, Yun-Ru, Lin, Ying-Ju |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746625/ https://www.ncbi.nlm.nih.gov/pubmed/26857472 http://dx.doi.org/10.1038/srep20665 |
Ejemplares similares
-
The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells
por: Lin, Jung-Chun, et al.
Publicado: (2017) -
RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis
por: Peng, Hui-Yu, et al.
Publicado: (2018) -
Impacts of Alternative Splicing Events on the Differentiation of Adipocytes
por: Lin, Jung-Chun
Publicado: (2015) -
Extracellular calcium modulates brown adipocyte differentiation and identity
por: Pramme-Steinwachs, Ines, et al.
Publicado: (2017) -
Follistatin promotes adipocyte differentiation, browning, and energy metabolism
por: Braga, Melissa, et al.
Publicado: (2014)