Functional transcription factor target discovery via compendia of binding and expression profiles

Genome-wide experiments to map the DNA-binding locations of transcription-associated factors (TFs) have shown that the number of genes bound by a TF far exceeds the number of possible direct target genes. Distinguishing functional from non-functional binding is therefore a major challenge in the stu...

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Detalles Bibliográficos
Autores principales: Banks, Christopher J., Joshi, Anagha, Michoel, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746627/
https://www.ncbi.nlm.nih.gov/pubmed/26857150
http://dx.doi.org/10.1038/srep20649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746627/
https://www.ncbi.nlm.nih.gov/pubmed/26857150
http://dx.doi.org/10.1038/srep20649

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