Cargando…

Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway

Terminally misfolded proteins are selectively recognized and cleared by the endoplasmic reticulum-associated degradation (ERAD) pathway. SEL1L, a component of the ERAD machinery, plays an important role in selecting and transporting ERAD substrates for degradation. We have determined the crystal str...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Hanbin, Sim, Hyo Jung, Song, Eun Kyung, Lee, Hakbong, Ha, Sung Chul, Jun, Youngsoo, Park, Tae Joo, Lee, Changwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746701/
https://www.ncbi.nlm.nih.gov/pubmed/27064360
http://dx.doi.org/10.1038/srep20261