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Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway

Terminally misfolded proteins are selectively recognized and cleared by the endoplasmic reticulum-associated degradation (ERAD) pathway. SEL1L, a component of the ERAD machinery, plays an important role in selecting and transporting ERAD substrates for degradation. We have determined the crystal str...

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Detalles Bibliográficos
Autores principales:	Jeong, Hanbin, Sim, Hyo Jung, Song, Eun Kyung, Lee, Hakbong, Ha, Sung Chul, Jun, Youngsoo, Park, Tae Joo, Lee, Changwook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746701/ https://www.ncbi.nlm.nih.gov/pubmed/27064360 http://dx.doi.org/10.1038/srep20261

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