Abnormalities in iNKT cells are associated with impaired ability of monocytes to produce IL‐10 and suppress T‐cell proliferation in sarcoidosis

Sarcoidosis is a multisystem granulomatous disorder characterized by marked T‐cell expansion of T helper 1 (Th1) cells. The cause of T‐cell overactivity is unknown. We hypothesized that interleukin‐10 (IL‐10) production by a yet undefined cell type might be defective, resulting in loss of regulation...

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Detalles Bibliográficos
Autores principales: Crawshaw, Anjali, Kendrick, Yvonne R., McMichael, Andrew J., Ho, Ling‐Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746743/
https://www.ncbi.nlm.nih.gov/pubmed/24723379
http://dx.doi.org/10.1002/eji.201344284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746743/
https://www.ncbi.nlm.nih.gov/pubmed/24723379
http://dx.doi.org/10.1002/eji.201344284

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