Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph(+) leukemia

BACKGROUND: Proteostasis is defined by the orchestrated control of anabolic and catabolic protein pathways. Disruption of proteostasis results in cell stress and adaptation to proteostasis imbalance is mediated by adaptive pathways such as the Heat Shock Response (including heat-shock proteins) or t...

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Detalles Bibliográficos
Autores principales: Vieri, Margherita, Geng, Huimin, Patterson, John B., Panse, Jens, Wilop, Stefan, Samali, Afshin, Chevet, Eric, Masouleh, Behzad Kharabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746784/
https://www.ncbi.nlm.nih.gov/pubmed/26862466
http://dx.doi.org/10.1186/s40164-016-0034-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746784/
https://www.ncbi.nlm.nih.gov/pubmed/26862466
http://dx.doi.org/10.1186/s40164-016-0034-5

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