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Soluble adenylyl cyclase mediates hydrogen peroxide-induced changes in epithelial barrier function
BACKGROUND: Elevated H(2)O(2) levels are associated with inflammatory diseases and H(2)O(2) exposure is known to disrupt epithelial barrier function, leading to increased permeability and decreased electrical resistance. In normal human bronchial epithelial (NHBE) cells, fully differentiated at the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746823/ https://www.ncbi.nlm.nih.gov/pubmed/26857816 http://dx.doi.org/10.1186/s12931-016-0329-4 |