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Mitochondrial and oxidative stress genes are differentially expressed in neutrophils of sJIA patients treated with tocilizumab: a pilot microarray study

BACKGROUND: Various pathways involved in the pathogenesis of sJIA have been identified through gene expression profiling in peripheral blood mononuclear cells (PBMC), but not in neutrophils. Since neutrophils are important in tissue damage during inflammation, and are elevated as part of the acute p...

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Detalles Bibliográficos
Autores principales: Omoyinmi, Ebun, Hamaoui, Raja, Bryant, Annette, Jiang, Mike Chao, Athigapanich, Trin, Eleftheriou, Despina, Hubank, Mike, Brogan, Paul, Woo, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746827/
https://www.ncbi.nlm.nih.gov/pubmed/26861863
http://dx.doi.org/10.1186/s12969-016-0067-7