Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

BACKGROUND: While many biological studies can be performed on cell-based systems, the investigation of molecular pathways related to complex human dysfunctions – e.g. neurodegenerative diseases – often requires long-term studies in animal models. The nematode Caenorhabditis elegans represents one of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746889/
https://www.ncbi.nlm.nih.gov/pubmed/26858201
http://dx.doi.org/10.1186/s13024-016-0083-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746889/
https://www.ncbi.nlm.nih.gov/pubmed/26858201
http://dx.doi.org/10.1186/s13024-016-0083-6

Ejemplares similares