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Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models
BACKGROUND: While many biological studies can be performed on cell-based systems, the investigation of molecular pathways related to complex human dysfunctions – e.g. neurodegenerative diseases – often requires long-term studies in animal models. The nematode Caenorhabditis elegans represents one of...
Autores principales: | Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746889/ https://www.ncbi.nlm.nih.gov/pubmed/26858201 http://dx.doi.org/10.1186/s13024-016-0083-6 |
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