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Resequencing and assembly of seven complex loci to improve the Leishmania major (Friedlin strain) reference genome

BACKGROUND: Leishmania parasites cause severe human diseases known as leishmaniasis. These eukaryotic microorganisms possess an atypical chromosomal architecture and the regulation of gene expression occurs almost exclusively at post-transcriptional levels. Accordingly, sequencing of the genome of L...

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Detalles Bibliográficos
Autores principales: Alonso, Graciela, Rastrojo, Alberto, López-Pérez, Sara, Requena, Jose M., Aguado, Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746890/
https://www.ncbi.nlm.nih.gov/pubmed/26857920
http://dx.doi.org/10.1186/s13071-016-1329-4