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Resequencing and assembly of seven complex loci to improve the Leishmania major (Friedlin strain) reference genome
BACKGROUND: Leishmania parasites cause severe human diseases known as leishmaniasis. These eukaryotic microorganisms possess an atypical chromosomal architecture and the regulation of gene expression occurs almost exclusively at post-transcriptional levels. Accordingly, sequencing of the genome of L...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746890/ https://www.ncbi.nlm.nih.gov/pubmed/26857920 http://dx.doi.org/10.1186/s13071-016-1329-4 |