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Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers

Despite significant advances in early detection and treatment, breast cancer still remains a major cause of morbidity and mortality for women. Our understanding of the molecular heterogeneity of the disease has significantly expanded over the past decade and the role of cell cycle signaling in both...

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Detalles Bibliográficos
Autores principales: Finn, Richard S., Aleshin, Alexey, Slamon, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746893/
https://www.ncbi.nlm.nih.gov/pubmed/26857361
http://dx.doi.org/10.1186/s13058-015-0661-5