Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways

BACKGROUND: Paris polyphylla is an oriental folk medicine that has anticancer activities both in vivo and in vitro. Polyphyllin VII (PP7), a pennogenyl saponin from P. polyphylla has been found to exert strong anticancer activity. However, the underlying mechanisms are poorly understood. In the pres...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Jia, Xuejing, Bao, Jiaolin, Chen, Shenghui, Wang, Kai, Zhang, Yulin, Li, Peng, Wan, Jian-Bo, Su, Huanxing, Wang, Yitao, Mei, Zhinan, He, Chengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746894/
https://www.ncbi.nlm.nih.gov/pubmed/26861252
http://dx.doi.org/10.1186/s12906-016-1036-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746894/
https://www.ncbi.nlm.nih.gov/pubmed/26861252
http://dx.doi.org/10.1186/s12906-016-1036-x

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