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Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

BACKGROUND: It has been shown that a random-effects framework can be used to test the association between a gene’s expression level and the number of DNA copies of a set of genes. This gene-set modelling framework was later applied to find associations between mRNA expression and microRNA expression...

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Detalles Bibliográficos
Autores principales: X. Menezes, Renée, Mohammadi, Leila, J. Goeman, Jelle, M. Boer, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746904/
https://www.ncbi.nlm.nih.gov/pubmed/26860128
http://dx.doi.org/10.1186/s12859-016-0926-8