LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation

BACKGROUND: Leucine-rich-alpha-2-glycoprotein 1 (LRG1) has been reported to be involved in several tumors, whether it participates in colorectal cancer (CRC) progression remains unclear. Here, we investigated the biological function and underlying molecular mechanisms of LRG1 in CRC. METHODS: The mR...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Zhu, Lingyin, Fang, Jingyuan, Ge, Zhizheng, Li, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746930/
https://www.ncbi.nlm.nih.gov/pubmed/26856989
http://dx.doi.org/10.1186/s13046-016-0306-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746930/
https://www.ncbi.nlm.nih.gov/pubmed/26856989
http://dx.doi.org/10.1186/s13046-016-0306-2

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