Feedback activation of neurofibromin terminates growth factor-induced Ras activation

BACKGROUND: Growth factors induce a characteristically short-lived Ras activation in cells emerging from quiescence. Extensive work has shown that transient as opposed to sustained Ras activation is critical for the induction of mitogenic programs. Mitogen-induced accumulation of active Ras-GTP resu...

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Detalles Bibliográficos
Autores principales: Hennig, Anne, Markwart, Robby, Wolff, Katharina, Schubert, Katja, Cui, Yan, Prior, Ian A., Esparza-Franco, Manuel A., Ladds, Graham, Rubio, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746934/
https://www.ncbi.nlm.nih.gov/pubmed/26861207
http://dx.doi.org/10.1186/s12964-016-0128-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746934/
https://www.ncbi.nlm.nih.gov/pubmed/26861207
http://dx.doi.org/10.1186/s12964-016-0128-z

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