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Generalization of Wei's urn design to unequal allocations in sequential clinical trials

Wei's urn design was proposed in 1987 for subject randomization in trials comparing m ≥ 2 treatments with equal allocation. In this manuscript, two modified versions of Wei's urn design are presented to accommodate unequal allocations. First one uses a provisional allocation of [Formula: s...

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Detalles Bibliográficos
Autores principales: Zhao, Wenle, Ramakrishnan, Viswanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747061/
https://www.ncbi.nlm.nih.gov/pubmed/26878069
http://dx.doi.org/10.1016/j.conctc.2015.12.007