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Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro

Clinical studies propose a causative link between the consumption of alcohol and the development and progression of liver disease in obese individuals. However, it is incompletely understood how alcohol and obesity interact and whether the combined effects are additive or synergistic. In this study,...

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Detalles Bibliográficos
Autores principales: Mahli, Abdo, Thasler, Wolfgang E., Patsenker, Eleonora, Müller, Sebastian, Stickel, Felix, Müller, Martina, Seitz, Helmut K., Cederbaum, Arthur I., Hellerbrand, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747167/
https://www.ncbi.nlm.nih.gov/pubmed/26497211