Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2

Nrf2 is a key transcription factor for genes coding for antioxidants, detoxification enzymes, and multiple drug resistance and it also confers resistance to anticancer drugs. Here, we hypothesized that mutant p53 could upregulate Nrf2 expression at the transcriptional level, thereby conferring cispl...

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Detalles Bibliográficos
Autores principales: Tung, Min-Che, Lin, Po-Lin, Wang, Yao-Chen, He, Tsung-Ying, Lee, Ming-Ching, Yeh, Sauh-Der, Chen, Chih-Yi, Lee, Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747182/
https://www.ncbi.nlm.nih.gov/pubmed/26497680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747182/
https://www.ncbi.nlm.nih.gov/pubmed/26497680

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