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STAT3 blockade enhances the efficacy of conventional chemotherapeutic agents by eradicating head neck stemloid cancer cell

Signaling transducer and activator 3 (STAT3) and cancer stem cells (CSCs) have garnered huge attention as a therapeutic focus, based on evidence that they may represent an etiologic root of tumor initiation and radio-chemoresistance. Here, we investigated the high phosphorylation status of STAT3 (p-...

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Detalles Bibliográficos
Autores principales: Bu, Lin-Lin, Zhao, Zhi-Li, Liu, Jian-Feng, Ma, Si-Rui, Huang, Cong-Fa, Liu, Bing, Zhang, Wen-Feng, Sun, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747200/
https://www.ncbi.nlm.nih.gov/pubmed/26556875