SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1

Iron metabolism is essential for many cellular processes including oxygen transport, respiration and DNA synthesis, and many cancer cells exhibit dysregulation in iron metabolism. Maintenance of cellular iron homeostasis is regulated by iron regulatory proteins (IRPs), which control the expression o...

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Detalles Bibliográficos
Autores principales: Jeong, Seung Min, Lee, Jaewon, Schmidt, Paul J., Fleming, Mark D., Haigis, Marcia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747239/
https://www.ncbi.nlm.nih.gov/pubmed/24909164
http://dx.doi.org/10.1038/onc.2014.124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747239/
https://www.ncbi.nlm.nih.gov/pubmed/24909164
http://dx.doi.org/10.1038/onc.2014.124

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