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Effect of SIRT1 Gene on Epithelial-Mesenchymal Transition of Human Prostate Cancer PC-3 Cells

BACKGROUND: The epithelial-mesenchymal transition (EMT) has been shown to be involved in the process of invasion and metastasis of prostate cancer. SIRT1 is the mammalian homologue of the silent information regulator 2 (Sir2) gene, and is abnormally expressed in prostate cancer cells. Therefore, it...

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Detalles Bibliográficos
Autores principales: Cui, Ying, Li, Jiang, Zheng, Fei, Ouyang, Yongri, Chen, Xi, Zhang, Lei, Chen, Yang, Wang, Lin, Mu, Shijie, Zhang, Huizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747318/
https://www.ncbi.nlm.nih.gov/pubmed/26847404
http://dx.doi.org/10.12659/MSM.895312