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A Simple Test of Class-Level Genetic Association Can Reveal Novel Cardiometabolic Trait Loci

BACKGROUND: Characterizing the genetic determinants of complex diseases can be further augmented by incorporating knowledge of underlying structure or classifications of the genome, such as newly developed mappings of protein-coding genes, epigenetic marks, enhancer elements and non-coding RNAs. MET...

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Detalles Bibliográficos
Autores principales: Qian, Jing, Nunez, Sara, Reed, Eric, Reilly, Muredach P., Foulkes, Andrea S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747495/
https://www.ncbi.nlm.nih.gov/pubmed/26859766
http://dx.doi.org/10.1371/journal.pone.0148218