Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita Cells

Dyskeratosis Congenita (DC) is an inherited multisystem premature aging disorder with characteristic skin and mucosal findings as well as a predisposition to cancer and bone marrow failure. DC arises due to gene mutations associated with the telomerase complex or telomere maintenance, resulting in c...

Descripción completa

Detalles Bibliográficos
Autores principales: Pereboeva, Larisa, Hubbard, Meredith, Goldman, Frederick D., Westin, Erik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747510/
https://www.ncbi.nlm.nih.gov/pubmed/26859482
http://dx.doi.org/10.1371/journal.pone.0148793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747510/
https://www.ncbi.nlm.nih.gov/pubmed/26859482
http://dx.doi.org/10.1371/journal.pone.0148793

Ejemplares similares