Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells

Flavokawain C (FKC) is a naturally occurring chalcone which can be found in Kava (Piper methysticum Forst) root. The present study evaluated the effect of FKC on the growth of various human cancer cell lines and the underlying associated mechanisms. FKC showed higher cytotoxic activity against HCT 1...

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Detalles Bibliográficos
Autores principales: Phang, Chung-Weng, Karsani, Saiful Anuar, Sethi, Gautam, Abd Malek, Sri Nurestri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747580/
https://www.ncbi.nlm.nih.gov/pubmed/26859847
http://dx.doi.org/10.1371/journal.pone.0148775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747580/
https://www.ncbi.nlm.nih.gov/pubmed/26859847
http://dx.doi.org/10.1371/journal.pone.0148775

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