What Population Reveals about Individual Cell Identity: Single-Cell Parameter Estimation of Models of Gene Expression in Yeast

Significant cell-to-cell heterogeneity is ubiquitously observed in isogenic cell populations. Consequently, parameters of models of intracellular processes, usually fitted to population-averaged data, should rather be fitted to individual cells to obtain a population of models of similar but non-ide...

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Detalles Bibliográficos
Autores principales: Llamosi, Artémis, Gonzalez-Vargas, Andres M., Versari, Cristian, Cinquemani, Eugenio, Ferrari-Trecate, Giancarlo, Hersen, Pascal, Batt, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747589/
https://www.ncbi.nlm.nih.gov/pubmed/26859137
http://dx.doi.org/10.1371/journal.pcbi.1004706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747589/
https://www.ncbi.nlm.nih.gov/pubmed/26859137
http://dx.doi.org/10.1371/journal.pcbi.1004706

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