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Galectin-8 promotes regulatory T cell differentiation by modulating IL-2 and TGFβ signaling

Galectins have emerged as potent immunoregulatory molecules that control chronic inflammation through distinct mechanisms. Galectin-8 (Gal-8), a tandem-repeat type galectin with unique preference for α2,3-sialylated glycans, is ubiquitously expressed, but little is known about its role in T cell dif...

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Detalles Bibliográficos
Autores principales: Sampson, James F., Suryawanshi, Amol, Chen, Wei-Sheng, Rabinovich, Gabriel A., Panjwani, Noorjahan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747822/
https://www.ncbi.nlm.nih.gov/pubmed/26282995
http://dx.doi.org/10.1038/icb.2015.72