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Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Kidney cells and tissues derived from human pluripotent stem cells (hPSCs) would enable organ regeneration, disease modeling, and drug screening in vitro. We established an efficient, chemically defined protocol for differentiating hPSCs into multipotent nephron progenitor cells (NPCs) that can form...

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Detalles Bibliográficos
Autores principales: Morizane, Ryuji, Lam, Albert Q., Freedman, Benjamin S., Kishi, Seiji, Valerius, M. Todd, Bonventre, Joseph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747858/
https://www.ncbi.nlm.nih.gov/pubmed/26458176
http://dx.doi.org/10.1038/nbt.3392