Cargando…

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

Kidney cells and tissues derived from human pluripotent stem cells (hPSCs) would enable organ regeneration, disease modeling, and drug screening in vitro. We established an efficient, chemically defined protocol for differentiating hPSCs into multipotent nephron progenitor cells (NPCs) that can form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morizane, Ryuji, Lam, Albert Q., Freedman, Benjamin S., Kishi, Seiji, Valerius, M. Todd, Bonventre, Joseph V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747858/ https://www.ncbi.nlm.nih.gov/pubmed/26458176 http://dx.doi.org/10.1038/nbt.3392

Ejemplares similares

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
por: Freedman, Benjamin S., et al.
Publicado: (2015)

Directed Differentiation of Pluripotent Stem Cells into Kidney
por: Morizane, Ryuji, et al.
Publicado: (2015)

Flow-enhanced vascularization and maturation of kidney organoids in vitro
por: Homan, Kimberly A., et al.
Publicado: (2019)

Generation of kidney tubular organoids from human pluripotent stem cells
por: Yamaguchi, Shintaro, et al.
Publicado: (2016)

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors
por: Bantounas, Ioannis, et al.
Publicado: (2018)

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids
por: Huang, Biao, et al.
Publicado: (2023)

3D kidney organoids for bench-to-bedside translation
por: Gupta✉, Navin, et al.
Publicado: (2020)

Strategies for Improving Vascularization in Kidney Organoids: A Review of Current Trends
por: Konoe, Ran, et al.
Publicado: (2023)

Applications of kidney organoids derived from human pluripotent stem cells
por: Kim, Yong Kyun, et al.
Publicado: (2018)

Meclizine Preconditioning Protects the Kidney Against Ischemia–Reperfusion Injury
por: Kishi, Seiji, et al.
Publicado: (2015)

Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery
por: Hiratsuka, Ken, et al.
Publicado: (2022)

ATP/ADP biosensor organoids for drug nephrotoxicity assessment
por: Susa, Koichiro, et al.
Publicado: (2023)

Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling
por: Uchimura, Kohei, et al.
Publicado: (2020)

Kidney Organoid Derived from Human Pluripotent and Adult Stem Cells for Disease Modeling
por: Kang, Hyun Mi
Publicado: (2023)

Gene Editing in Pluripotent Stem Cells and Their Derived Organoids
por: Zhou, Hang, et al.
Publicado: (2021)

Engraftment of Kidney Organoids In Vivo
por: Freedman, Benjamin S., et al.
Publicado: (2023)

In vitro induction and in vivo engraftment of kidney organoids derived from human pluripotent stem cells
por: Zhang, Denglu, et al.
Publicado: (2020)

Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering
por: Silva, Teresa P., et al.
Publicado: (2019)

Human Pluripotent Stem Cell-Derived Alveolar Organoid with Macrophages
por: Seo, Ha-Rim, et al.
Publicado: (2022)

The “3Ds” of Growing Kidney Organoids: Advances in Nephron Development, Disease Modeling, and Drug Screening
por: Chambers, Brooke E., et al.
Publicado: (2023)

Modeling endodermal organ development and diseases using human pluripotent stem cell-derived organoids
por: Pan, Fong Cheng, et al.
Publicado: (2020)

Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling
por: Jansen, Jitske, et al.
Publicado: (2022)

Deep learning predicts the differentiation of kidney organoids derived from human induced pluripotent stem cells
por: Park, Keonhyeok, et al.
Publicado: (2023)

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells
por: Kumar, Santhosh V., et al.
Publicado: (2019)

Detection of Hematopoietic Stem Cell Transcriptome in Human Fetal Kidneys and Kidney Organoids Derived From Human Induced Pluripotent Stem Cells
por: Hwang, Jin Wook, et al.
Publicado: (2021)

3D proximal tubule-on-chip model derived from kidney organoids with improved drug uptake
por: Aceves, Jeffrey O., et al.
Publicado: (2022)

In vitro generation of human pluripotent stem cell derived lung organoids
por: Dye, Briana R, et al.
Publicado: (2015)

Challenges for the Applications of Human Pluripotent Stem Cell-Derived Liver Organoids
por: Chang, Mingyang, et al.
Publicado: (2021)

Reversing Epithelial Polarity in Pluripotent Stem Cell-Derived Intestinal Organoids
por: Kakni, Panagiota, et al.
Publicado: (2022)

Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids
por: Gaykema, Lonneke H., et al.
Publicado: (2023)

Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells
por: Garreta, Elena, et al.
Publicado: (2022)

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids
por: Capeling, Meghan M., et al.
Publicado: (2019)

Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
por: Sarrafha, Lily, et al.
Publicado: (2023)

Live functional assays reveal longitudinal maturation of transepithelial transport in kidney organoids
por: Rizki-Safitri, Astia, et al.
Publicado: (2022)

Modeling human development and disease in pluripotent stem cell-derived gastric organoids
por: McCracken, Kyle W., et al.
Publicado: (2014)

Pluripotent stem cell‐derived retinal organoids for disease modeling and development of therapies
por: Kruczek, Kamil, et al.
Publicado: (2020)

Generation of human pluripotent stem cell-derived fused organoids with oligodendroglia and myelin
por: Kim, Hyosung, et al.
Publicado: (2021)

In Vitro Recapitulation of Neuropsychiatric Disorders with Pluripotent Stem Cells-Derived Brain Organoids
por: Gulimiheranmu, Maisumu, et al.
Publicado: (2021)

Induced Pluripotent Stem Cell-Derived Organoids: Their Implication in COVID-19 Modeling
por: Csöbönyeiová, Mária, et al.
Publicado: (2023)

Modeling of FAN1-Deficient Kidney Disease Using a Human Induced Pluripotent Stem Cell-Derived Kidney Organoid System
por: Lim, Sun Woo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_uqtvp4hcpqekf3h0mdvan922b0