Nonsense-Mediated Decay Restricts LncRNA Levels in Yeast Unless Blocked by Double-Stranded RNA Structure

Antisense long non-coding (aslnc)RNAs represent a substantial part of eukaryotic transcriptomes that are, in yeast, controlled by the Xrn1 exonuclease. Nonsense-Mediated Decay (NMD) destabilizes the Xrn1-sensitive aslncRNAs (XUT), but what determines their sensitivity remains unclear. We report that...

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Detalles Bibliográficos
Autores principales: Wery, Maxime, Descrimes, Marc, Vogt, Nicolas, Dallongeville, Anne-Sophie, Gautheret, Daniel, Morillon, Antonin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747904/
https://www.ncbi.nlm.nih.gov/pubmed/26805575
http://dx.doi.org/10.1016/j.molcel.2015.12.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747904/
https://www.ncbi.nlm.nih.gov/pubmed/26805575
http://dx.doi.org/10.1016/j.molcel.2015.12.020

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