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Signal Increase on Unenhanced T1-Weighted Images in the Rat Brain After Repeated, Extended Doses of Gadolinium-Based Contrast Agents: Comparison of Linear and Macrocyclic Agents

OBJECTIVES: In this prospective preclinical study, we evaluated T1-weighted signal intensity in the deep cerebellar nuclei (CN) and globus pallidus (GP) up to 24 days after repeated administration of linear and macrocyclic gadolinium-based contrast agents (GBCAs) using homologous imaging and evaluat...

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Detalles Bibliográficos
Autores principales: Jost, Gregor, Lenhard, Diana Constanze, Sieber, Martin Andrew, Lohrke, Jessica, Frenzel, Thomas, Pietsch, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747981/
https://www.ncbi.nlm.nih.gov/pubmed/26606548
http://dx.doi.org/10.1097/RLI.0000000000000242