A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ(+) CMI responses protects against a genital infection in minipigs

Chlamydia is the most widespread sexually transmitted bacterial disease and a prophylactic vaccine is highly needed. Ideally, this vaccine is required to induce a combined response of Th1 cell-mediated immune (CMI) response in concert with neutralizing antibodies. Using a novel Göttingen minipig ani...

Descripción completa

Detalles Bibliográficos
Autores principales: Bøje, Sarah, Olsen, Anja Weinreich, Erneholm, Karin, Agerholm, Jørgen Steen, Jungersen, Gregers, Andersen, Peter, Follmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748142/
https://www.ncbi.nlm.nih.gov/pubmed/26268662
http://dx.doi.org/10.1038/icb.2015.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748142/
https://www.ncbi.nlm.nih.gov/pubmed/26268662
http://dx.doi.org/10.1038/icb.2015.79

Ejemplares similares