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A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ(+) CMI responses protects against a genital infection in minipigs
Chlamydia is the most widespread sexually transmitted bacterial disease and a prophylactic vaccine is highly needed. Ideally, this vaccine is required to induce a combined response of Th1 cell-mediated immune (CMI) response in concert with neutralizing antibodies. Using a novel Göttingen minipig ani...
Autores principales: | Bøje, Sarah, Olsen, Anja Weinreich, Erneholm, Karin, Agerholm, Jørgen Steen, Jungersen, Gregers, Andersen, Peter, Follmann, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748142/ https://www.ncbi.nlm.nih.gov/pubmed/26268662 http://dx.doi.org/10.1038/icb.2015.79 |
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